Functional and effective connectivity of motor areas in parkinsons patients in comparision to healthy subjects belonging to two different groups of age.

Functional and effective connectivity of motor areas in parkinsons patients in comparision to healthy subjects belonging to two different groups of age. - BiSyT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00005635

Enrollment

Registered

2014-03-11

Start date

2014-02-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G20

Interventions

Group 1: young, healthy subjects (128-channel EEG-recording during the performance of a tapping-task) Group 2: old, healthy subjects (128-channel EEG-recording during the performance of a tapping-task

Eligibility

Sex/Gender

All

Age

20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Healthy subjects: • male and female paticipants, age 20 to 40 mother language: german • male and female paticipants, age 50 to 70, mother language: german • capability of signing an informed consent Parkinson's patients: • male and female patients with the clinical diagnosis of an idopathic parkinson syndrom • age between 40 and 80, motherlangue: german • capability of signing an informed consent

Exclusion criteria

Exclusion criteria: Healthy participants: • diagnosis of an idiopathic parkinson syndrom or any other neurological disease • participants with a contraindication for an MR-scan like metal parts inside the body, i.e. cardiac pacemaker, stents etc. • participants that take drugs regularly which influence the nervous system and which can not be stopped the evening befor the experiment • pragnent or breast feeding mothers Parkinson's patients: • non- "sui juris" patients, underaged persons as well as subjects which are judically sent to an institution • patients that suffer from another neurological disease apart from Parkinsons like Epilepsy, Alzheimers or Dystonia • patients with claustrophobia • participants with a contraindication for an MR-scan like metal parts inside the body, i.e. cardiac pacemaker, stents etc. • patients with irregular MR-scans like ischemia, cerebral atrophy etc. • former surgeries on the head especially for the implantation of electrodes for Deep Brain Stimulation Therapy • pronounced head tremor that does not allow laying still in the MR and produces artefacts during EEG recordings • presense of psychiatric diseases • impaired vision or hearing defect that may hinder the testing • pregnant or breast feeding mothers

Design outcomes

Primary

Measure	Time frame
Pathological coupling of motor areas depending on the complexity of a Tapping-task in Parkinson's patients.	—

Secondary

Measure	Time frame
Prediction of behavioral errors during the performance of a Tapping-task in Parkinson's patients.	—

Countries

Germany

Contacts

Public ContactElfriede Stubbs

Uniklinik Köln, NeurologieArbeitsgruppe für Bewegungsstörungen und Tiefe Hirnstimulation

elfriede.stubbs@uk-koeln.de022147898842

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026