G35.1 G35.3
Conditions
Interventions
Group 1: standard treatment plus a mindfulness-based group training (duration of 6 weeks, once a week for one hour),
Group 2: standard treatment (immunmodulatory medication, physiotherapy)
Sponsors
Neurologische Universitätsklinik Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The patient is willing to and physically and mentally capable to participate in the study 2. age 18 up to max. 65 years 3. confirmed diagnosis of relapse remitting or secondary progressive multiple sclerosis, according McDonald criteria 2010 4. EDSS score of 0 up to max. 5.5 5. A diagnosis of a chronic fatigue-syndrom as a symptom of MS (fatigue questionnaire of the MS council as diagnostic tool) 6. severity of fatigue of at least 4 (Fatigue severity scale) 7. if treatment with immunmodulatory medication, then for at least 6 weeks
Exclusion criteria
Exclusion criteria: 1. no severe or untreated depression or psychiatric disease 2. no chronic sleep disturbances 3. no severe acute concomitant diseases which require acute medical treatment (e.g. tumor or encephalitis) 4. no untreated metabolism disease such as hypothyreosis or dysbalanced electrolytes 5. no anemia (Hb < 12g/dl) or known iron deficits 6. no intake of any sedating medication (analgetics containing opioid or antihistaminica with a sedating effect) 7. no relapse within the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The training can significantly improve the patients' cognitive performance. This will be quanitified with standardized neuropsychological tests before and after 6-week-training: The d2-attention stress test and the VLMT verbal learn and memorizing test | — |
Secondary
| Measure | Time frame |
|---|---|
| The training can significantly reduce the patients' fatigue symptoms and improve the patients'quality of life. This will be quanitified with standardized questionnaires: fatigue severity scale (FSS) and the SF-36 quality of life questionnaire. The Questionnaire will be filled out before and after the 6-week training | — |
Countries
Germany
Contacts
Public ContactGisa Schluh
Neurologische Universitätsklinik
Outcome results
None listed