E66 E11.9
Conditions
Interventions
Group 1: Interventional (normobaric hypoxia 12Vol% O2) randomized placebo controlled trial with healthy moderately obese (non severe obese) persons with increased risk for diabetes type II based on in
Sponsors
Hermann BUhl Institut für Hypoxie und Schlafmedizinforschung der Universität Innsbruck
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Physical ability to perform at 100 Watts for 15 min on a cycle ergometer
Exclusion criteria
Exclusion criteria: Heart failure stages NyHa 3 and 4, diabetes with complications, malign tumors, non- ambulant surgery within the last six month, COPD Gold 3 and 4, smoking> 2cigarettes/day, missing physical ability to perform at least 15 at 100 Watts on the cycle ergometer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bodyweight/BMI after 6 month i.e. 48 units of 3 hours time spent in normobaric hypoxia for each individual. | — |
Secondary
| Measure | Time frame |
|---|---|
| Exrra- and intra cellular leptin, HbA1c, serumlipids, body fat mass (%) after 6 month i.e. 48 units of 3 hours time spent in normobaric hypoxia for each individual. | — |
Countries
Germany
Contacts
Public ContactStephan Pramsohler
Hermann Buhl Institut für Hypoxie und Schlafmedizinforschung gGmbH
Outcome results
None listed