depression, quality of life F48.0
Conditions
Interventions
Group 1: Biofeedback therapy is considered to be a specific method of cognitive behavioral therapy. It allows simultaneous feedback of physiological functions and allows patients to influence that phy
Sponsors
Universitätsklinikum Tübingen
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Clinically evaluated, persistent and chronic fatigue (6months or longer); four or more of the following symptoms: impaired memory or concentration, sore throat, tender cervical or axilliary lymph nodes, muscle pain, multi-joint pain, new headaches, unrefreshing sleep and post-exertion malaise.
Exclusion criteria
Exclusion criteria: somatic or medical conditions explaining fatigue (e.g. can-cer), substance abuse, primary psychiatric disorder (e.g. schizophrenia), major depression or anxiety disorder, on-going psychotherapy or activation programme, a body-mass index (BMI) lower than 18.5kg/m² or higher than 35kg/m², and male sex]
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue (Questionnaire); pre, post, 5month-follow-up Fatigue was measured by the “multidimensional fatigue inventory” (MFI, Gaab & Ehlert, 2005). It measures fatigue on five subscales (general fatigue, physical fatige, reduced activity, reduced motivation, mental fatigue) and allows the accumulation of a total score. MFI was assessed pre and post intervention and in a 5 month-follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life, depression, stress/ability to relax (questionnaires); pre, post, 5month-follow-up. Physiological stress reaktion (orthostatic test, salivary cortisol); pre, post. Quality of life - that is, physical and mental functioning - was assessed by the “Short Form General Health Survey” (SF36; Bullinger & Kirchberger, 1998). Depression was assessed using the “Patient Health Questionnaire” (PHQ-9; Löwe et al., 2002). Ability to relax was assessed by the “Symptom Checklist for Perceived Relaxation” (ASS-Sym; Krampen 2006). Assessment of questionnaires took place before and after intervention and at a five-month follow-up. Physiological stress reaction was measured pre and post intervention by orthostatic test and by salivary cortisol level (8 measurements a day once before and once after intervention). | — |
Countries
Germany
Contacts
Public ContactPetra Windthorst
Universitätsklinikum Tübingen
Outcome results
None listed