severe chronic periodontitis K05.3
Conditions
Interventions
Group 1: control group: scaling and root debridement
Group 2: test group 1: scaling and root debridement
plus adjunctive phododynamic therapy
treatments (immediately after scaling and root debrideme
Sponsors
Danube Private University (DPU)
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: - age of 30–70 years - present diagnosis of severe chronic periodontitis of at least 6 teeth with a probing pocket depth (PPD) >5 mm, bleeding - written informed consent - Plaque Index (PI) < 1 and Gingiva Index (GI) <1 after pretreatment
Exclusion criteria
Exclusion criteria: - major systemic illnesses (i.e., diabetes mellitus, cancer, HIV, tuberculosis, bone metabolic diseases or disorders that compromise wound healing, rheumatoid arthritis, lupus erythematosus) - radiation, or immunosuppressive therapy - pregnant or breastfeeding woman - smoking behaviour - use of long-term administration of anti-inflammatory medications - antibiotic therapies in the previous 6 months - teeth with furcation involvement - radiologically diagnosted combined endodontic-periodontic lesions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| probing pocket depth, measured with computer administrated probe (Florida-Probe) at baseline, as well as 3, 6 and 12 months after therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| Bleeding on Probing (number of sites with bleeding after Probing) measured with computer adnmistraded probe at baseline, 3, 6 and 12 months after therapy, periodontopathogenic bacteria measured with a chairside test at baseline, 2 weeks, 6 and 12 months after therapy, inflammatory markers from gingival cevicular fluid | — |
Countries
Germany
Contacts
Public ContactDaniela Hoedke
Charité Universitätsmedizin BerlinCC3 ZahnklinikAbteilung für Parodontologie und synoptische Zahnmedizin
Outcome results
None listed