C34
Conditions
Interventions
Group 1: Patients suspected of/or diagnosed with lung cancer:
- before surgery: clarification, informed consent, questionnaire, EKG, spirometry, taking blood, etc.
- intraoperative: BAL collection
- a
Sponsors
Universitätsklinikum Erlangen
Anästhesie
Abteilung Molekulare Pneumologie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Further inclusion criteria Patients with suspicion of/ or diagnosed lung tumor with medical indication for 1) VATS (video-assisted thoracoscopic surgery) or open surgical procedure on the lung and 2) taking blood and/or 3) performance of a bronchoscopy with bronchoalveolar lavage
Exclusion criteria
Exclusion criteria: - limited coagulation (Quick50s, thrombocytes 1,5mg/dl) - pregnancy - nursing period - limited or non-existent compliance ability - amyloidosis (SSA), family-related polyneuropathy (FAP) and family-related cardiomyopathy - other severe diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • Identification of targeted immunotherapy for patients with lung cancer • recurrence rate and survival (within one year) | — |
Secondary
| Measure | Time frame |
|---|---|
| • Identification of immunological and clinical parameters for early diagnosis/ prognosis of patients with lung cancer • Characterisation of the relation between nutritional status and immun status in patients with lung cancer Surrogate-Markers • CD4+ T-Zellen, CD8+T-Zellen, TGFß, IL 2, IL 10, IL 12, Transthyretin level in serum, Tbet, T regulatory cells, etc. | — |
Countries
Germany
Contacts
Public ContactHoria Sirbu
Universitätsklinikum ErlangenThoraxchirurgische Abteilung
Outcome results
None listed