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Prospective study on the relevance of the detection of respiratory viruses in pharyngeal aspirates in healthy individuals

Prospective study on the relevance of the detection of respiratory viruses in pharyngeal aspirates in healthy individuals

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00005367
Enrollment
222
Registered
2013-10-17
Start date
2013-10-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Volunteer J00-J06

Interventions

Group 1: The participants are asked to provide pharyngeal aspirates twice within 3 weeks and are questioned regarding symptoms of a common cold. In case of acute respiratory infections within the foll

Sponsors

Universitätsklinikum Jena
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - >17 years of age - written informed consent

Exclusion criteria

Exclusion criteria: - no informed consent - pulmonary disease of any kind with or without medication -Disease that leads to immunosuppression at study entry or within the past 5 years including diabetes mellitus -immunosuppressive or immunemodulating medication at study entry or within the past 5 years

Design outcomes

Primary

MeasureTime frame
prevalence of positive results for viral pathogens in pharyngeal aspirates from healthy donors determined by multiplex PCR at timepoint 0, 3 weeks later and at the onset of an acute respiratory infection

Secondary

MeasureTime frame
correlation of positive results for viral pathogens determined by PCR with symptoms, stress level and smoking at timepoint 0, 3 weeks later and at the onset of an acute respiratory infection

Countries

Germany

Contacts

Public ContactRamona Kraft

Universitätsklinikum Jena

Ramona.Kraft@med.uni-jena.de03641-9324210

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 1, 2026