Z31.9
Conditions
Interventions
Group 1: Using the semen sample achieved on the day of follicle aspiration SP was extracted by centrifugation and was stored in the incubator. Remaining to the SP a syringe was transferred to the cli
Sponsors
Landes Frauen und Kinderklinik Linz
Eligibility
Sex/Gender
Female
Age
18 Years to 41 Years
Inclusion criteria
Inclusion criteria: All woman were 18-41 years of age, nulliparous, non-smoker with a BMI under 35 and undergoing their first or second IVF/ICSI cycle at our clinic
Exclusion criteria
Exclusion criteria: Exclusion criteria including no embryo transfer due to ovarian hyperstimulation syndrome or fertilization failure, hepatitis B, hepatitis C, HIV, leucocytospermia and men with less than 0,5ml of SP. All patients with endometrial- such as polyps, or myometrial anomalies (fibroids) and congenital uterine abnormalities, or Ashermann- syndrome were excluded. Another exclusion criteria was required application of SP.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The following primary endpoints were defined: change of vascularization flow index (VFI) of the subendometrium between oocyte pick- up (baseline) and embryo transfer (1); change of vascularization index (VI) of the subendometrium between oocyte pick- up (baseline) and embryo transfer (2); change of flow index (FI) of the subendometrium between oocyte pick- up (baseline) and embryo transfer (3); change of vascularization flow index (VFI) of the endometrium between oocyte pick- up (baseline) and embryo transfer (4); change of vascularization index (VI) of the endometrium between oocyte pick- up (baseline) and embryo transfer (5); change of flow index (FI) of the endometrium between oocyte pick- up (baseline) and embryo transfer (6); change of endometrial volume between oocyte pick- up (baseline) and embryo transfer (7). Measurement was done 30 minutes prior to oocyte pick- up and 30 minutes prior to embryo transfer, using a GE Voluson I Ultrasound machine: GE Kretz, Austria. Volumetric and vascular measurements were then undertaken using Virtual Organ Computer- aided AnaLyses (VOCAL, GE Kretz). | — |
Secondary
| Measure | Time frame |
|---|---|
| Subendometrial Vaskularizations-Flow-Index at examination U2 (Embryo- or Blastocysttransfer), subendometrial Flow-Index U2, subendometrial Vaskularizationindex U2. Endometrial Vaskularization-Flow-Index U2, endometrial Flow-Index U2, endometrial Vaskularizationindex U2. Endometrium volume at examination U2. Measurement was done 30 minutes prior to oocyte pick- up and 30 minutes prior to embryo transfer, using a GE Voluson I Ultrasound machine: GE Kretz, Austria. Volumetric and vascular measurements were then undertaken using Virtual Organ Computer- aided AnaLyses (VOCAL, GE Kretz). Pregnancy rate was evaluated four weeks after embryo transfer (U3) (Final examination) via transvaginal ultrasound examination. Lifebirth- rate was evaluated using the austrian birthregister of in vitro fertilization. | — |
Countries
Austria
Contacts
Public ContactRichard Mayer
Landes Frauen- und Kinderklinik Linz
Outcome results
None listed