case-control study on how the type and duration of antimicrobial treatment effects the probability of recurring infections endoprothesis or fracture fixation devices

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00005283

Enrollment

1000

Registered

2013-09-03

Start date

2013-03-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T84.5 T84.6 T84.7

Interventions

Group 1: Cases will be patients with a failed therapy which means patients with a recurring infection one year after the last surgical debridement. Routine data records from the study centers will b

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Infected fracture fixation device (i.e., plate-screw-combination) of a long bone (i.e., humerus, forearm, femur, tibia, or fibula), of the ankle joint (inside and outside ankle), of the heel bone proven by CDC criteria and / or tissue samples and / or surgical findings OR Infected total knee or hip arthroplasty proven by CDC criteria and / or tissue samples and / or surgical findings

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
Duration of the systemic antimicrobial treatment after the last surgical intervention.	—

Secondary

Measure	Time frame
Kind of systemic antimicrobial therapy ( monotherapy or combined treatment, dose, application, substances)	—

Countries

Germany

Contacts

Public ContactRomy Spitzmüller

Universitätsmedizin Greifswald, Klinik und Poliklinik für Chirurgie, Abteilung für Unfall- und Wiederherstellungschirurgie

romy.spitzmueller@uni-greifswald.de03834 86 6125

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026