Epidemiology of multiresistant gram-negative bacteria (MRGN) in the context of hospital treatment at university hospital Jena – a prospective cohort study

Epidemiology of multiresistant gram-negative bacteria (MRGN) in the context of hospital treatment at university hospital Jena – a prospective cohort study - ESBL

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00005273

Enrollment

2000

Registered

2013-09-04

Start date

2013-09-24

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Within the study no specific disease pattern is investigated.

Interventions

Group 1: The occurrence and the risk of transmission of multiresistant gram-negative bacteria (MRGN) are examined in a total of 2000 hospitalized patients that fulfil the inclusion criteria. To it, on

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - at least age of 18 years - expected hospitalisation more than 48 hours - admission from extern

Exclusion criteria

Exclusion criteria: not any

Design outcomes

Primary

Measure	Time frame
-Rate of colonisation [n/1000 patients] with MRGN during hospital stay via quotient from number of patients that are colonised with a new MRGN bacteria at hospital discharge by number of total patients at hospital discharge	—

Secondary

Measure	Time frame
- Rate of nosocomial infection during hospital stay (Total, With MRGN (PFGE analysis), Selective for Full-Analysis-Setnegativ and Full-Analysis-SetMRGN) - Acquirement of MRGN per 1000 antibiotic-days in hospital (per class of antibiotics, per substance, per antibiotic combination) - Rate of colonisation with MRGN from that patients that are colonised with MRGN at hospital discharge (via quotient from patients that are colonised with MRGN at 6 month after hospital discharge by number of patients that are colonised at hospital discharge) - clonality of all detected MRGN (PFGE-analysis)	—

Measure

Time frame

- Rate of nosocomial infection during hospital stay (Total, With MRGN (PFGE analysis), Selective for Full-Analysis-Setnegativ and Full-Analysis-SetMRGN) - Acquirement of MRGN per 1000 antibiotic-days in hospital (per class of antibiotics, per substance, per antibiotic combination) - Rate of colonisation with MRGN from that patients that are colonised with MRGN at hospital discharge (via quotient from patients that are colonised with MRGN at 6 month after hospital discharge by number of patients that are colonised at hospital discharge) - clonality of all detected MRGN (PFGE-analysis)

—

Countries

Germany

Contacts

Public ContactStefan Hagel

Universitätsklinikum JenaZentrum für Infektionsmedizin und Krankenhaushygiene

stefan.hagel@med.uni-jena.de+49 3641 9-324590

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026