F20.0 F20.1
Conditions
Interventions
Group 1: active transcranial random noise stimulation. 20 min duration/intervention, 20 interventions in two weeks (2 stimulations per day, monday-friday).
Technical aspects: high frequency (HF
100-640 Hz), current strength 2mA, offset at 1 mA.
Group 2: sham transcranial random noise stimulation. 20 min duration/intervention, 20 interventions in two weeks (2 stimulations per day, monday-frid
Sponsors
Klinik für Psychiatrie, Psychotherapie und Psychosomatik der LMU München
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Diagnosis of a paranoid or hebephrenic schizophrenia according to ICD-10 criteria. Baseline stability of medication for at least three weeks. Baseline stability of psychopathological symptoms for at least one week.
Exclusion criteria
Exclusion criteria: Other psychiatric disorders, severe internal or neurologic disordrs, seizures, implants, cancers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant reduction in the score of the Positive and Negative Symptom Scale (PANSS) as a measure for the global severity of the disorder and the Scale for the Assessment of Negative Symptoms (SANS) as a measure of the negative symptoms from Baseline to immediately after the 20th stimulation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Significant improvement of the Verbal Learning and Memory Test (VLMT), n-back-test, self-ordered pointing task (SOPT), all three measuring short memory and working memory, and Trail Making Test (TMT) as a measure of working memory, from baseline to immediately after the 20th stimulation. | — |
Countries
Germany
Contacts
Public ContactUlrich Palm
Klinik für Psychiatrie, Psychotherapie und Psychosomatik der LMU München
Outcome results
None listed