The Impact of Dialysate Magnesium on the Calcification Propensity of Serum

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00005230

Enrollment

Registered

2013-08-16

Start date

2013-08-19

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N18.5

Interventions

Group 1: cross-over design Exposition to a low (0.5mmol) magnesium concentration in dialysate (for a total of 12 treatment sessions in week 1-2 (6 sessions) and week 7-8 (6 sessions)) Group 2: Expo

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: chronic dialysis for more than 3 months

Exclusion criteria

Exclusion criteria: Gravidity Age < 18y

Design outcomes

Primary

Measure	Time frame
Calcification Propensity of serum determined by a new nephelometric test (precipitations Time T50) at 13 different time points in the study: Baseline (day 1 of week 1), T2 (day 1 of week 2), T3 (day 1 of week 3), T4 (day 2 of week 3), T5 (day 3 of week 3), T6 (day 1 of week 4), T7 (day 1 of week 5), T8 (day 1 of week 6), T9 (day 1 of week 7), T10 (day 2 of week 7), T11 (day 3 of week 7), T12 (day 1 of week 8) Baseline, T2 and T9-T12 with 0.5mmol Magnesium and T3-T8 with 0.75mmol Of note: Day one, two or three corresponds to the first, second or third dialysis session in the corresponding week	—

Measure

Time frame

Calcification Propensity of serum determined by a new nephelometric test (precipitations Time T50) at 13 different time points in the study: Baseline (day 1 of week 1), T2 (day 1 of week 2), T3 (day 1 of week 3), T4 (day 2 of week 3), T5 (day 3 of week 3), T6 (day 1 of week 4), T7 (day 1 of week 5), T8 (day 1 of week 6), T9 (day 1 of week 7), T10 (day 2 of week 7), T11 (day 3 of week 7), T12 (day 1 of week 8) Baseline, T2 and T9-T12 with 0.5mmol Magnesium and T3-T8 with 0.75mmol Of note: Day one, two or three corresponds to the first, second or third dialysis session in the corresponding week

—

Countries

Switzerland

Contacts

Public ContactStefan Farese

Abteilung für Nephrologie, Medizinische Klinik Bürgerspital Solothurn

stefan.farese@spital.so.ch+41 32 627 42 11

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026