Contrast-Induced Nephropathy N99.0
Conditions
Interventions
Group 1: preconditioning
ischemic conditioning caused by 4 cycles of inflation with 50 mmHg above systolic blood pressure and deflation for 5 minutes each using blood pressure cuff.
The procedure is done BEFORE contrast expo
ischemic conditioning caused by 4 cycles of inflation with 50 mmHg above systolic blood pressure and deflation for 5 minutes each using blood pressure cuff.
The procedure is done AFTER contrast expos
ischemic conditioning caused by 4 cycles of inflation with 50 mmHg above systolic blood pressure and deflation for 5 minutes each using blood pressure cuff.
The procedure is usually done after contra
Sponsors
Universität des Saarlandes
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Written consent. Chronic kidney disease (CKD), defined as a serum-creatinin > 1,4 mg/dl. Planned contrast-exposure and indication for nephroprotection.
Exclusion criteria
Exclusion criteria: No written consent. Patients with AV-Shunt. Required dialysis after contrast-exposure. Affection for haematoma. Thrombophilia. Stenosis or occlusive disease of vessels of the upper limb. Systolic blood pressure > 180 mmHg.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lack of kidney function loss after contrast-exposition, defined as lack of or mild decrease in renal function, characterized by an decrease of glomerular filtration rate estimated by using creatinine- and cystatin C- serum level, evaluated on three days after conditioning (dialy). | — |
Secondary
| Measure | Time frame |
|---|---|
| no secundary outcome defined | — |
Countries
Germany
Contacts
Public ContactStephen Zewinger
Univesitätsklinikum des Saarlandes, Innere Medizin IV
Outcome results
None listed