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transcranial random noise stimulation for the treatment cognitive symptoms in the cluster of negative syndrome in schizophrenia.

transcranial random noise stimulation for the treatment cognitive symptoms in the cluster of negative syndrome in schizophrenia. - tRNS in schizophrenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00005200
Enrollment
30
Registered
2013-08-20
Start date
2013-10-01
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F20.0 F20.1

Interventions

Group 1: active transcranial random noise stimulation. 20 min duration/intervention, 10 interventions in two weeks. technical aspects: High frequency (hf
100-640 Hz), current strength 2 mA, offset at 1 mA. Group 2: sham transcranial random noise stimulation. 20 min duration/intervention, 10 interventions in two weeks, technical aspects: high frequency
100-640 Hz), current strength 2 mA, offset at 1 mA.

Sponsors

Klinik für Psychiatrie, Psychotherapie und Psychosomatik der LMU München
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Diagnosis of a paranoid or hebephrenic schizophrenia according to ICD-10 criteria. Basline stability of medication for at least one week. Baseline stability of psychopathological symptoms for at least one week.

Exclusion criteria

Exclusion criteria: Other psychiatric diagnoses, severe internal or neurologic disorders, seizures, implants, cancers.

Design outcomes

Primary

MeasureTime frame
(I) Significant improvement of verbal learning and memory test (VLMT) and n-back-test and (II) reduction of score in the Positive and Negative Symptom Scale (PANSS) from Baseline to immediately after the 10th intervention.

Secondary

MeasureTime frame
(I) Reduction of score in the Scale for the Assessment of Negative Symptoms (SANS) and (II) improvement in the self ordered pointing task (SOPT) and trail making test (TMT) from Baseline to immediately after the 10th intervention.

Countries

Germany

Contacts

Public ContactJana Nolden

Klinik und Poliklinik für Psychiatrie und Psychotherapie

jana.nolden@med.uni-muenchen.de089/5160-5511

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026