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The effect of platelet transfusions on platelet function after P2Y12 receptor mediated platelet inhibition in whole blood in – vitro (Pilot Study).

The effect of platelet transfusions on platelet function after P2Y12 receptor mediated platelet inhibition in whole blood in – vitro (Pilot Study). - P2YAntagonists

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00005196
Enrollment
36
Registered
2013-09-03
Start date
2013-09-09
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I25.9

Interventions

Group 1: Blood Samples from Patients on Clopidogrel Therapy will be used for in-vitro addition of platelet concentrate equivalents. Group 2: Blood Samples from Patients on Prasugrel Therapy will be u

Sponsors

Medizinische Universität Wien
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients on Clopidogrel, Prasugrel or Ticagrelor + Aspirin Therapy

Exclusion criteria

Exclusion criteria: inadequate ADP Receptor inhibition while on Clopidogrel/Prasugrel/Ticagrelor Therapy

Design outcomes

Primary

MeasureTime frame
AUC (ADP) in Multiple Electrode Aggregometry prior to and after the Transfusion of 2 or 4 Platelet Concentrate Equivalents

Secondary

MeasureTime frame
AUC (TRAP & ASPI) in Multiple Electrode Aggregometry prior to and after the Transfusion of 2 or 4 Platelet Concentrate Equivalents

Countries

Austria

Contacts

Public ContactDieter Adelmann

Medizinische Universität Wien

dieter.adelmann@meduniwien.ac.at+431404004150

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026