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NEUROvitalis Plus: cognitive training effects of a neuropsychological program in combination with a physical training and nutrition education

NEUROvitalis Plus: cognitive training effects of a neuropsychological program in combination with a physical training and nutrition education - NV+ Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00005194
Enrollment
72
Registered
2013-12-06
Start date
2012-10-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy older adults, healthy cognitive aging

Interventions

Group 1: The arm NEUROvitalis will be trained with the cognitive training NEUROvitalis. NEUROvitalis is a neuropsychological, cognitive training program for the improvement of the cognitive functions

Sponsors

Universität Vechta, Institut für Gerontologie und Center für Neuropsychologische Diagnostik und Intervention
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 85 Years

Inclusion criteria

Inclusion criteria: cognitive healthy elderly of all educational backgrounds and sufficient verbal skills in German

Exclusion criteria

Exclusion criteria: at T0: when participant suffers a neurological or psychiatric disease or alcohol or drug abuse or when vision, hearing or speech is impaired or the achieved score is 19 in BDI-II; exclusion of statistical analysis if < 11 sessions (11 sessions match ca. 80% of attendance time) are visited

Design outcomes

Primary

MeasureTime frame
Improvements in cognitive subdomains: attention (Brief test of attention); memory (DemTect, Subtests word list and delayed recall; Complex-Figure-Test); visuo-construction (Complex-Figure-Test); working memory (DemTect, Subtest digit span backwards); word fluency (DemTect, Subtest supermarket/animals; Regensburger Wortflüssigkeits-Test , different subtests); processing speed (Trail Making Test-A; Stroop Test); executive functions (Trail Making Test-B; Stroop Test; BADS, Subtests Key Search, Zoo Map and DEX), and in overall cognitive function (DemTect). The primary outcome will be assessed at times T0 (pretest), T1 (posttest after the intervention), T2 (follow-up after one year), T3 (follow-up after two years).

Secondary

MeasureTime frame
Improvements in 1. neurophysiological parameters: assessment of the APO-E- and the BDNF-Genotype, assessment of the level of BDNF, IGF-1, VEGF in the blood. 2. non-cognitive domains: quality of life (WHOQOL-BREF), physical fitness (Senior Fitness Test), motivational questionnaires, questionnaire about nutrition. All secondary outcomes will be assessed at times T0 (pretest) and T1 (posttest after the intervention). At T2 (follow-up after one year) and T3 (follow-up after two years) alone the cognitive subdomains will be assessed.

Countries

Germany

Contacts

Public ContactJulia Rahe

Universität Vechta, Institut für Gerontologie und Center für Neuropsychologische Diagnostik und Intervention

julia.rahe@uni-vechta.de+49 4441 15730

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 4, 2026