J96.0 J18.9
Conditions
Interventions
Group 1: The assignment of patients to the order in which the three oxygen applicators is applied will be randomized. Each intervention is preceded by a 15-minute baseline period, in which oxygen is a
Sponsors
Universitätsklinikum Tübingen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age > 18 years, signs of acute respiratory failure (tachypnea, dyspnea) with paO2 < 55 mmHg under room air
Exclusion criteria
Exclusion criteria: - cardiac pulmonary edema - COPD and /or ventilatory failure - hemodynamic instability - contraindications to NIV - impaired consciousness or desorientation - inability to give informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| At the end of each 30 min intervention phase the following primary endpoints are measured: •Respiratory rate •Arterial oxygen partial pressure (paO2) •Dyspnea (10 point numeric Borg – Scale) •Patient comfort (10 point numeric scale) At the end of the investigation the patients rate all three devices using German school grades (1=very good, 6= failed) und can choose one device for further treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| At the end of each 30 min intervention phase the following secondary endpoints are measured: • Arterial CO2 partial pressure (paCO2) • Heart rate • Blood pressure • Peripheral oxygen saturation (SpO2) | — |
Countries
Germany
Contacts
Public ContactReimer Riessen
Internistische Intensivstation93 Department für Innere Medizin Universitätsklinikum Tübingen
Outcome results
None listed