E11
Conditions
Interventions
Group 1: Placebo: cellulose, 15 capsules/d (5 capsules with breakfast, 5 capsules with lunch, and 5 capsules with dinner), contains 5mg lutein/d for 14 days
Group 2: verum: perilla frutescens (freeze
Sponsors
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin der TU München
Lehrstuhl für Ernährungsmedizin
Eligibility
Sex/Gender
Male
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: healthy volunteers: no medication, BMI between 20 and 40 kg/m2 diabetic patients: moderate diabetes mellitus type 2 treated by diet alone or with oral antidiabetic agents (stable medication for at least 3 months), HbA1c < 8.0%, BMI between 20 and 40 kg/m2
Exclusion criteria
Exclusion criteria: insulin or glucocorticoid treatment, smoking, dietary supplements, known allergy to the tested food itself or a component, severe chronic disease (gastrointestinal, renal, pulmonary, cardiac, neurological, and psychiatric diseases), or myocardial infarction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| zeaxanthin and lutein (measured by HPLC), malondialdehyde (measured by HPLC), lag-phase and Trolox equivalent antioxidative capacity (measured photometrically) measured at the beginning and at the end of the intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| ß-carotene, cryptoxanthin, a-carotene, lycopene, vitamin E (all measured by HPLC) measured at the beginning and at the end of the intervention | — |
Countries
Germany
Contacts
Public ContactThomas Skurk
Technischen Universität München ZIEL-Institute for Food and Health Core Facility für Humanstudien
Outcome results
None listed