Efficacy of pregabalin in prevention of acute postoperative pain after oral surgery treatment

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

DRKS

Registry ID

DRKS00005085

Enrollment

Registered

2013-07-26

Start date

2013-09-03

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-operative pain R52.9

Interventions

Group 1: Lyrica (pregabalin) 1 tablet of 150 mg 1 hour preoperatively p.o. Group 2: Placebo

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with anaesthesiologist's approval, classified in ASA 1 and ASA 2 group.

Exclusion criteria

Exclusion criteria: Patients with proven allergy to pregabalin, uncontrolled cardiovascular disease or diabetes, kidney disorders, liver disease, ones treated for chronic pain states, pregnant women and patients who took any analgesic 24 hours before the planned surgical treatment.

Design outcomes

Primary

Measure	Time frame
Visual analogue scale (VAS) will be used to measure the postoperative pain score, 2,6,12 and 24 hours after oral surgery treatments.	—

Secondary

Measure	Time frame
Time and dose of rescue analgesics will be observed after a surgical treatment. Any of the side effects will be monitored and reported to the drug agency and manufacture representative.	—

Countries

Croatia

Contacts

Public ContactJosip Biocic

Univeristy Hospital Dubrava, Department of Oral and Maxillofacial Surgery

biocic@sfzg.hr+385-95-9101-802

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026