Effects of respiratory system mechanics / ventilation at increasing of positive end-expiratory pressure in lung-healthy patients during elective surgeries with anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00005058

Enrollment

Registered

2013-06-10

Start date

2013-06-12

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients during surgery

Interventions

Group 1: Observational group: In patients with no known lung injury during mechanical ventilation for elective surgery respiratory system mechanics ans ventilation distribution in the lungs are invest

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: patients with non-injured lungs during surgery

Exclusion criteria

Exclusion criteria: pregnancy, known lung injury, terminal state of desease, unstable spinal injury, pacemakre, implanted cardioverter of defibrillator, brain injury, congenital heart defect, missing confirmed consent

Design outcomes

Secondary

Measure	Time frame
Using a device for electical impedance tomography the impedacnes inside the thorax are measured. In an offline analysis the ventilation distribution in the lungs will be determined.	—

Primary

Measure	Time frame
The temporal courses of pressure and flow rate are recorded as measured from the ventilator. After the experiments the intratidal profile of compliance is calculated from these data in an offline analysis.	—

Countries

Germany

Contacts

Public ContactSteffen Wirth

Anästhesiologische Universitätsklinik

steffen.wirth@uniklinik-freiburg.de0761/23380

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026