Neuropsychological intervention in Parkinson's disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00004978

Enrollment

300

Registered

2013-05-29

Start date

2013-05-31

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G20

Interventions

Group 1: NEUROvitalis: a structured neuropsychological group training containing psychoeducation, specific training of different cognitive functions (memory, attention, executive functions) in individ

Eligibility

Sex/Gender

All

Age

50 Years to 90 Years

Inclusion criteria

Inclusion criteria: Patients with a clinical diagnosis of idiopathic Parkinson's disease (UK Brain Bank Criteria; Hughes et al., 1992). Patients, who score I-III on Hoehn and Yahr scale. Patients, without dementia (without cognitive impairment, mild cognitive impairment in accord with Petersen at most) with a Demtect score > 8 and MMSE > 24. Male and female patients. Patients at the age of 50 to 90. Patients without significant impairment of hearing or sight. Native german-speaking patients, or patients with a sufficient knowledge of the german language. Patients, who are able to participate in the training session (90 minutes, 2 times a week over 6 weeks). Patients, who participate in minimum 8 of 12 sessions. Patienten, who give their consent to participate in the study and who sign informed consent.

Exclusion criteria

Exclusion criteria: Patients with suspected dementia (DemTect < 9, MMSE < 25). Patients with another neurological (e.g. epilepsy, Alzheimer's disease) or psychiatric disease (schizophrenia). Patients with drug or alcohol abuse (at present or in the past).

Design outcomes

Primary

Measure	Time frame
Effects on cognitive total scores (DemTect, MMSE). The primary outcomes are examined at T0 (pretest), T1 (examination after the intervention or after 6 weeks without intervention), T2 (one year follow-up), T3 (2 year follow-up).	—

Secondary

Measure	Time frame
Effects on 1. cognitive subdomains: attention (Brief test of attention); verbal short and long term memory (DemTect Memo-test); visual memory (Rey-Osterrieth figure / Modified Taylor figure); visuoconstructive skills (Rey-Osterrieth figure / Modified Taylor figure); working memory (DemTect). verbal fluency (DemTect, FAS-test); subjective memory impairment (Memory Complaint Questionnaire); subjective attention impairment ("Fragebogen erlebter Defizite der Aufmerksamkeit"). 2. non-cognitive parameters: depression (BDI-II); quality of life (PDQ-39). Secondary outcomes are examined at T0 (pretest), T1 (examination after the intervention or after 6 weeks without intervention), T2 (one year follow-up), T3 (2 year follow-up).	—

Measure

Time frame

Effects on 1. cognitive subdomains: attention (Brief test of attention); verbal short and long term memory (DemTect Memo-test); visual memory (Rey-Osterrieth figure / Modified Taylor figure); visuoconstructive skills (Rey-Osterrieth figure / Modified Taylor figure); working memory (DemTect). verbal fluency (DemTect, FAS-test); subjective memory impairment (Memory Complaint Questionnaire); subjective attention impairment ("Fragebogen erlebter Defizite der Aufmerksamkeit"). 2. non-cognitive parameters: depression (BDI-II); quality of life (PDQ-39). Secondary outcomes are examined at T0 (pretest), T1 (examination after the intervention or after 6 weeks without intervention), T2 (one year follow-up), T3 (2 year follow-up).

—

Countries

Germany

Contacts

Public ContactAnnette Petrelli

Uniklinik Köln Klinik und Poliklinik für Neurologie AG Neuropsychologie

annette.petrelli@uk-koeln.de0221-47889127

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026