Genetic, age, gender and environmental factors that modify immuno-responses and the development of allergic asthma during the school age in childhood.

Genetic, age, gender and environmental factors that modify immuno-responses and the development of allergic asthma during the school age in childhood. - AGENDAS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004927

Enrollment

Registered

2013-05-16

Start date

2016-01-25

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J45

Interventions

Group 1: Children with allergic asthma, Childrens Age 6-10 year: Taking of a blood sample and measurement of the fractionated exhaled NO by FeNo-Monitoring machine and nose smear test. No futher test

Eligibility

Sex/Gender

All

Age

6 Years to 10 Years

Inclusion criteria

Inclusion criteria: - Written informed consent from the child’s parents/guardian’s - Age 6-10 years (beginning at the day of the 6th birthday and ending at the day of the 10th birthday) - Gestational age 36 weeks or above - A diagnosis of allergic asthma within the last 2 years or bronchial hyperreactivity - The child is able to perform a body plethysmography - The legal custodian has the verbal, writing and mental ability to understand the intent and character of the study Control group: - Age 6-10 years - No history of allergic asthma and bronchial hyperreactivity

Exclusion criteria

Exclusion criteria: - Severe/brittle asthma - Other chronic respiratory diseases (CF, BPD, immunodeficiencies) except allergic rhinitis - Other chronic diseases or chronic medication use except atopic exzema

Design outcomes

Primary

Measure	Time frame
WHAT: Genexpression from blood lymphocytes(Array Human Genetic) WHEN: one-time test	—

Countries

Germany

Contacts

Public ContactTheodor Zimmermann

Universitätsklinikum Erlangen Kinder- und Jugendklinik

Theodor.Zimmermann@uk-erlangen.de09131 85-33118

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026