healthy volunteers
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: healthy men and women; 18 -80 years of age; non-smokers; participants who are able to conduct all tests; participants who gave written and informed consent.
Exclusion criteria
Exclusion criteria: smoker; volunteers with regular drug use; pregnant or breast feeding women; volunteers with diseases of the cardiovascular system, lungs, GI-trakt, metabolism, skin, viscera, nervous system, and infectious or immunological diseases in therapeutic need; allergy against PABA (p-Aminobenzoesäure); Intolerance against FINALGON; volunteers with tumours; volunteers with acute or chronic infectious diseases; volunteers with drug or alcohol abuse; volunteers who may not adhere to the study protocol; volunteers that gave no wrtitten consent; institutionalised patients in mental hospitals.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Human metabolome in fasting plasma (single morning blood sample) and 24h urine (previous day) (analysis by NMR, GCxGC-MS, LC-MS/MS) | — |
Secondary
| Measure | Time frame |
|---|---|
| nutrient intake (24h-recall questionaire), physical activity (accelerometer, questionaire), aerobic exercise capacity (cycle ergometry), anthopometry/body composition (DEXA), blood pressure (RR). One-time examinations under standardised conditions and adherence to a strict shedule on the day before, during and after blood sampling. | — |
Countries
Germany
Contacts
Max Rubner-Institut