Skip to content

The Karlsruhe Metabolomics Project

The Karlsruhe Metabolomics Project - KarMeN

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00004890
Enrollment
300
Registered
2013-04-10
Start date
2012-05-02
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy volunteers

Interventions

Group 1: Healthy volunteers are examined by means of anthropometric, physiological and clinical methods. They answer questionaires on nutrition and physical activity. Blood and urine is analysed by me

Sponsors

Max Rubner-Institut
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: healthy men and women; 18 -80 years of age; non-smokers; participants who are able to conduct all tests; participants who gave written and informed consent.

Exclusion criteria

Exclusion criteria: smoker; volunteers with regular drug use; pregnant or breast feeding women; volunteers with diseases of the cardiovascular system, lungs, GI-trakt, metabolism, skin, viscera, nervous system, and infectious or immunological diseases in therapeutic need; allergy against PABA (p-Aminobenzoesäure); Intolerance against FINALGON; volunteers with tumours; volunteers with acute or chronic infectious diseases; volunteers with drug or alcohol abuse; volunteers who may not adhere to the study protocol; volunteers that gave no wrtitten consent; institutionalised patients in mental hospitals.

Design outcomes

Primary

MeasureTime frame
Human metabolome in fasting plasma (single morning blood sample) and 24h urine (previous day) (analysis by NMR, GCxGC-MS, LC-MS/MS)

Secondary

MeasureTime frame
nutrient intake (24h-recall questionaire), physical activity (accelerometer, questionaire), aerobic exercise capacity (cycle ergometry), anthopometry/body composition (DEXA), blood pressure (RR). One-time examinations under standardised conditions and adherence to a strict shedule on the day before, during and after blood sampling.

Countries

Germany

Contacts

Public ContactAnita Kriebel

Max Rubner-Institut

anita.kriebel@mri.bund.de0721 6625413

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 5, 2026