The impact of different humidification techniques in newly tracheotomized patients - an ex vivo study

The impact of different humidification techniques in newly tracheotomized patients - an ex vivo study - high flow airway humidification (Airvo)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00004865

Enrollment

Registered

2013-06-04

Start date

2013-06-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Z93.0

Interventions

Group 1: Provisioning of cold air humidification system to the newly tracheotomized patient. Group 2: Provisioning of high-flow warm air humidification system to the newly tracheotomized patient.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Any therapy which includes a planned tracheotomy.

Exclusion criteria

Exclusion criteria: no consent regarding participation, known ciliary dysfunction, patients with tracheostoma in past medical history

Design outcomes

Primary

Measure	Time frame
Ciliary function, measured using videodocumented ciliary beat frequency and a so called visual integrity index (VI) of tracheal epithelial cells harvested at day 1, 3, 5, 7,9,11,13 after tracheotomy.	—

Secondary

Measure	Time frame
daily episodes of medical intervention at the tracheostoma / trachea because of respiratory / tracheal complaints. Number of required tracheostoma suctions because of excessive mucus. Frequency of tracheitis. Subjective complaints in terms of a questionnaire assessing respiratory / lower airway function.	—

Countries

Germany

Contacts

Public ContactJ. Ulrich Sommer

Univ.-HNO-Klinik Mannheim

ulrich.sommer@uni-heidelberg.de+49-621-383-1600

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026