Streptococcus pneumoniae: Nasopharyngeal and Oropharyngeal Carriage in Nursing Home Residents

Streptococcus pneumoniae: Nasopharyngeal and Oropharyngeal Carriage in Nursing Home Residents - PneumoCaRe

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004833

Enrollment

500

Registered

2013-04-05

Start date

2013-04-29

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

naso-/oropharyngeal pneumococcal carriage naso-/oropharyngeal bacterial carriage

Interventions

Group 1: Observational group: Nursing home residents of whom an oropharyngeal and a nasopharyngeal swab will be taken

multimorbidity and functional status will be assessed by several validated instruments

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: • Female and male nursing home residents in the age of 65 years and above living in one of the participating nursing homes • Willingness to participate of nursing home resident or his/her legal guardian • Written informed consent of participants or their legal guardians

Exclusion criteria

Exclusion criteria: • Lack of power of judgement (Mini Mental State Examination (MMSE) < 24 points) without legal guardian • Refusal of participation by legal guardian • actual Medication with immunosuppressant drugs with systemic effect • Antibiotic use up to 10 days preceding swab • Hospital stay up to 2 weeks preceding swab • Nursing home residents with diagnosis of end stage malignoma • Participation on other clinical trials during this observational study

Design outcomes

Primary

Measure	Time frame
• Nasopharyngeal and oropharyngeal carriage of Streptococcus pneumoniae • Serotype-specific nasopharyngeal and oropharyngeal carriage of Streptococcus pneumoniae Exploratively: Nasopharyngeal and oropharyngeal carriage of Streptococcus pneumoniae adjusted for multimorbidity and functional status at day of swab taking Evaluation of functional status by comprehensive geriatric assessment (i. e. geriatric screening (Lachs), mini mental state examination (Folstein)), evaluation of multimorbidity by Cumulative Illness Rating Scale, geriatric version.	—

Measure

Time frame

• Nasopharyngeal and oropharyngeal carriage of Streptococcus pneumoniae • Serotype-specific nasopharyngeal and oropharyngeal carriage of Streptococcus pneumoniae Exploratively: Nasopharyngeal and oropharyngeal carriage of Streptococcus pneumoniae adjusted for multimorbidity and functional status at day of swab taking Evaluation of functional status by comprehensive geriatric assessment (i. e. geriatric screening (Lachs), mini mental state examination (Folstein)), evaluation of multimorbidity by Cumulative Illness Rating Scale, geriatric version.

—

Secondary

Measure	Time frame
• Other bacterial nasopharyngeal and oropharyngeal carriage Exploratively: Other bacterial nasopharyngeal and oropharyngeal carriage than Streptococcus pneumoniae adjusted for multimorbidity and functional status at day of swab taking Safety: • Adverse events occuring within 24 hours following the swab	—

Countries

Germany

Contacts

Public ContactAnja Kwetkat

Klinik für Geriatrie Universitätsklinikum Jena

anja.kwetkat@med.uni-jena.de03641934901

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026