Troponin measurements from patients in the Emergency Department regardless what their chief complaints are. There is no need of specific chief complaints because the study does not aim at specific diseases.
Conditions
Interventions
Group 1: Measurement of troponin T on a point-of-care device (Radiometer) from routine blood (whole blood) in the emergency department.
Group 2: Measurement of troponin I on a point-of-care device (Ra
Sponsors
Charité - Universitätsmedizin Berlin
Medizinische Klinik m.S. Kardiologie
Arbeitsbereich Notfallmedizin CVK und CCM
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients in the Emergency Department that receive a Troponin measurement.
Exclusion criteria
Exclusion criteria: no exclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of measurement discrepancies utilizing parallel measurement of cardiac troponin T and I performed on the POCT device used in the emergency department (EDTA, AQT-90, Radiometer) and high sensitive troponin T performed in the central laboratory (lithium-heparin, Cobas, Roche). All measurements are performed during regular patient treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Detection and quantification of possible sample mixups in troponin measurements in the emergency department using described thresholds and additional measurement od the two biomarkers total protein and pseudocholinesterase. All measurements are performed during regular patient treatment. Additionally a comparison of the diagnostic accuracy of the troponin tests used will be performed concerning the diagnosis of acute myocardial infarction. Theses analyses will be performed after finalized recruitment. | — |
Countries
Germany
Contacts
Public ContactJulia Searle
Charité - Universitätsmedizin Berlin Medizinische Klinik m.S. Kardiologie Arbeitsbereich Notfallmedizin Campus Virchow Klinikum
Outcome results
None listed