Healthy adults C82 C83
Conditions
Interventions
Group 1: Patients, treated because of indolent NHL. 5 out of the 10 patients exercise 30 minutes on a bycyleergometer after randomization. After the work-out cognition tests will be performed. Blood s
Sponsors
Deutsche Sporthochschule Köln, Institut für Kreislaufforschung und Sportmedizin
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The end of the first line Chemotherapy should not be dated back longer than 24 weeks in both patient groups Written consent
Exclusion criteria
Exclusion criteria: • Hb III • Symptomatic Coronary heart disease • COPD • Respiratory Globa linsufficiens • Medical treatment of Fatigue • cerebral cramping • fatigable drug intake • medical or psychological state that prevents patient to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| H3K9 und H4K5 Acetylation in NK-cells and CD8+ T-Lymphocytes Measure Timepoinzs: T1 Pre (before endurance session and cognition testing), T2 Post (after endurance and cognition testing) Methods: PBMC Isolation, MACS Sorting, DAB Staining, ImageJ Valuation | — |
Secondary
| Measure | Time frame |
|---|---|
| Cytokines (TNF alpha, MIF) > T1 and T2 Fatigue > pre Intervention (T1) > Questionaires (BFI, MFI-20, EORTC QLQ-C30) EEG (IAF) > during rest, endurance exercise and cognition tests Executive function > Wiener Testsystem | — |
Countries
Germany
Contacts
Public ContactPhilipp Zimmer
Deutsche Sporthochschule Köln, Insitut für Kreislaufforschung und Sportmedizin, Abteilung für molekulare und zelluläre Sportmedizin
Outcome results
None listed