Intracameral concentrations of the fibrinolytic system components in patients with age-related macular degeneration.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004679

Enrollment

100

Registered

2013-01-29

Start date

2010-02-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H35.3

Interventions

Group 1: Patients suffering from exsudative age-related macular degeneration. Aspiration of anterior chamber fluid during routine cataract removal procedure. Group 2: Patients suffering from dry age-r

Eligibility

Sex/Gender

All

Age

40 Years to 100 Years

Inclusion criteria

Inclusion criteria: age-related macular degeneration, cataract

Exclusion criteria

Exclusion criteria: neoplasias high myopia patient younger 40 years other eye diseases (diabetic retinopathy, h/o retinal detachment, uveitis, glaucoma)

Design outcomes

Primary

Measure	Time frame
Detection of intrcameral plasminogen activity	—

Secondary

Measure	Time frame
Detection of concentrations and activities of different fibrinolytic system components. (Plasminogen-activator-inhibitor I (PAI-1), alpha2-antiplasmin, plasmin-a2-antiplasmin complex (PAP) )	—

Countries

Germany

Contacts

Public ContactThomas Bertelmann

UKGM GmbH, Standort Marburg, AUgenklinik

thomas.bertelmann@staff.uni-marburg.de06421-5862600

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026