The prevalence of HPV infection in patients with carcinoma of unknown primary site in head and neck region in Germany

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004657

Enrollment

200

Registered

2015-02-12

Start date

2012-07-09

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C80

Interventions

Group 1: Determination of p16 and HPV PCR in cervical lymph node metastasis (FFPE) and correlation to survival and smoking habits.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Cervical CUP-Syndrome without primary within 6 months after diagnosis. paraffin-embedded tissue of the lymph node metastasis available. >18 years. patients informed consent.

Exclusion criteria

Exclusion criteria: Primary tumor found within 6 months after diagnosis. No paraffin-embedded tissue of the lymph node metastasis available. <18 years. No patients informed consent.

Design outcomes

Primary

Measure	Time frame
HPV (human papillomavirus) and p16 status in cervical metastasis	—

Secondary

Measure	Time frame
overall survival, recurrent-free survival	—

Countries

Germany

Contacts

Public ContactRainald Knecht

University Medical Center Hamburg-Eppendorf ENT,Head and Neck Department

r.knecht@uke.de+49 40 7410 52360

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026