Influence of 10 Hz rTMS and noradrenergic modulation on motor learning in healthy humans

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00004653

Enrollment

Registered

2013-01-16

Start date

2012-05-28

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Group 1: Atomoxetine + real-10Hz-rTMS (single dose of 60 mg Atomoxetine per os) Group 2: Placebo + real-10Hz-rTMS Group 3: Atomoxetine + sham-rTMS (single dose of 60 mg Atomoxetine per os) Group 4: Pl

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: healthy subjects, right handed, age between 18 - 45 years

Exclusion criteria

Exclusion criteria: left-handed, neurological diseases, psychiatric diseases, other medical diseases, brain injury, stroke, febrile seizures in the childhood, psychotropic medication, fine motor skills, implanted devices like cardiac pacemaker, any metal in the head, pregnancy, lactation

Design outcomes

Primary

Measure	Time frame
Assessment of motor potentials evoked by transcranial magnetic stimulation, potentials were recorded with surface EMG-electrodes from the first dorsal interosseus muscle of the left hand (peak-to-peak-amplitudes in mV): resting motor threshold, short-intracortical-inhibition, intracortical facilitation, stimulus response curve Measured by the raw data of the fingertapping task: target score (total number of correct responses), execution time (time required to the subsequent correct response in ms)	—

Measure

Time frame

Assessment of motor potentials evoked by transcranial magnetic stimulation, potentials were recorded with surface EMG-electrodes from the first dorsal interosseus muscle of the left hand (peak-to-peak-amplitudes in mV): resting motor threshold, short-intracortical-inhibition, intracortical facilitation, stimulus response curve Measured by the raw data of the fingertapping task: target score (total number of correct responses), execution time (time required to the subsequent correct response in ms)

—

Countries

Germany

Contacts

Public ContactMatthias Sczesny-Kaiser

Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH

matthias.sczesny-kaiser@rub.de02343023258

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026