Multicentric investigation of behavioral and neuronal influences of adverse childhood experiences on mother-child interaction

Multicentric investigation of behavioral and neuronal influences of adverse childhood experiences on mother-child interaction - UBICA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00004649

Enrollment

240

Registered

2013-01-31

Start date

2013-01-01

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sexual or physical childhood abuse T74.1 T74.2

Interventions

Group 1: Parent-Child-Interaction-Therapy (Hembree-Kigin et al., 1995): 1 50min session/week

12 sessions

participation at at least 8 sessions required Group 2: Individual Stress Management Training (modified after Kaluza, 2011): 1 50min session/week

participation at at least 8 sessions required

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Mothers with and without adverse childhood experiences and with 5-12 years old children

Exclusion criteria

Exclusion criteria: Participants with contraindications against MRI will be excluded from the study. Participants with claustrophobia, acute suicidality or drug dependency will be also excluded. In addition, control-dyads must not have any traumatic childhood experiences.

Design outcomes

Primary

Measure	Time frame
Mother: Changes in maternal sensitivity from baseline to follow-up I (after intervention) (EA-score). Child: Changes in the child's well-being from baseline to follow-up I (after intervention) (KIDS-SCREEN-score).	—

Secondary

Measure	Time frame
Mother: Changes in maternal sensitivity, Intrusivity and hostility from baseline to follow-up II (6 months after intervention) in EA-scores as well as changes in maternal psychopathology from baseline to follow-up I (after intervention) and II (6 months after intervention) (HAMD, SCL-90-R, BDI-II, IRI, PSI, scores) and in maternal abuse risk (EBSK, score). Child: Changes in the child's responsiveness (EA-scales) and the child's well-being (KIDS-SCREEN score) from baseline to follow-up II (6 months after intervention) as well as changes in the child's behavior from baseline to follow-up I (after intervention) and II (6 months after intervention) (CBCL, TRF, scores).	—

Measure

Time frame

Mother: Changes in maternal sensitivity, Intrusivity and hostility from baseline to follow-up II (6 months after intervention) in EA-scores as well as changes in maternal psychopathology from baseline to follow-up I (after intervention) and II (6 months after intervention) (HAMD, SCL-90-R, BDI-II, IRI, PSI, scores) and in maternal abuse risk (EBSK, score). Child: Changes in the child's responsiveness (EA-scales) and the child's well-being (KIDS-SCREEN score) from baseline to follow-up II (6 months after intervention) as well as changes in the child's behavior from baseline to follow-up I (after intervention) and II (6 months after intervention) (CBCL, TRF, scores).

—

Countries

Germany

Contacts

Public ContactFelix Bermpohl

Psychiatrische Universitätsklinik der Charité im St. Hedwig-Krankenhaus

felix.bermpohl@charite.de030-2311-2949

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026