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Agitation, aggression and arrousal in patients suffering from psychosis - comparison parenteral benperidol, ziprasidone and aripiprazole

Agitation, aggression and arrousal in patients suffering from psychosis - comparison parenteral benperidol, ziprasidone and aripiprazole

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00004620
Enrollment
90
Registered
2013-01-21
Start date
2012-10-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F20 F25

Interventions

Group 1: benperidole Evaluation of retrospective analysis of efficacy, side effects and acceptance of treated persons Group 2: intramuscular aripiprazole Evaluation of retrospective analysis of effica

Sponsors

LVR-Klinik Köln
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: diagnosis (ICD10) of schizophrenia (F20) or schizoaffective disorder (F25) BPRS of at least 12 points age of 18 up to 65 years written informed consent on participation to the study

Exclusion criteria

Exclusion criteria: Patients which do not fullfill the criteria (ICD10) for schizophrenia or schizoaffective disorder. Age under 18 or over 65 years. A BPRS of lower then 12 points.

Design outcomes

Primary

MeasureTime frame
1. Change of BPRS at first and at last administration of parenteral treatment 2. Change of positive and negative syndrome scale - excited component at first and at last administration of parenteral treatment

Secondary

MeasureTime frame
1. total number of parenteral injections 2. duration of parenteral incejtions in days 3. duration of treatment in hospital after last parenteral injection 4. dose of sedatives given to patients in chlorpromazin equivalents 5. side effects and acceptance rated by UKU Rating Scale 6. acceptance of patients the day after the last injection by visual analog scale

Countries

Germany

Contacts

Public ContactDirk Reske

LVR-Klinik Köln

dirk.reske@lvr.de02218993797

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026