P27.1
Conditions
Interventions
Group 1: Preterms with a gestational age up to 32+0 weeks will be prospectively included in the study. Urine, tracheal aspirates and serum samples will be obtained in clinical routine. Lung function a
Sponsors
Ludwig-Maximilian Universität München
Perinatalzentrum Großhadern
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Included will be all preterm infants up 32+0 weeks gestational age, that are born and treated in the Perinatal Center Grosshadern or the Department of Neonatology in Giessen (UKGM)where parental informed consent can be obtained. Gestational age will be determined by the gynecologist either by calculation or sonographic determination. If gestational age is unclear, sonographic findings from the early pregnancy will serve as reference value.
Exclusion criteria
Exclusion criteria: - Severe congenital abnormalities with cardiopulmonary dysfunction that cannot be survived (Ebstein anomaly, hypoplastic left ventricle, pulmonary hypoplasia following ahydramnion, Total Anomalous Pulmonary Venous Connection) - Congenital diaphragmatic hernia, trisomie 13 and 18 and metabolic defects that lead to severe compromise for the organism - Palliativ treatment decided in the first 10 minutes of life
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Statistical significance for a biomarker and proval with a different method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reaching the limitations of the approved n-number. | — |
Countries
Germany
Contacts
Public ContactAnne Hilgendorff
Ludwig-Maximilian Universität München Perinatalzentrum Großhadern
Outcome results
None listed