F15.2 F12.2
Conditions
Interventions
Group 1: probands with cannabinoid dependence: fMRT: two task to test the processing of social-emotional cues. During the fMRI-procedure the probands will take part in an animated ball tossing game (C
Sponsors
Ministerium für Innovation, Wissenschaft, Forschung und Technologie
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Cannabinoid-dependence, Amphetamin-dependence according to the criteria of the ICD-10: control group: persons without any mental disorder and no consumption of any illicit drugs more than five times in life
Exclusion criteria
Exclusion criteria: Epilepsy, apoplexia, multiple sclerosis, myasthenia gravia, coronary heart disease, Diabetes Mellitus, chronic obstructive pulmonary diseases, psychiatric medication, long-term medication (exception: contraceptives), consumption of legal or illegal psychotropic drugs during the last 28 days (exception: nicotine, alcohol), alcohol consumption for the day of the procedure, heart/head operation, hearing aids, cardiac pacemaker, drug pumps, removable dental protheses, metal parts in or around the body (e. g. metal shivers, artificial hip-joints, acupuncture devices, implanted, electrodes, unremovable piercings, metal-containing tattoos), claustrophobia, pregnancy, lactation, unsecure contraception, axis I or II mental disorder (DSM-IV) except cannabis or amphetamin dependence. consumption of acohol more than twice a month excessively or frequent heavy drinkung during the past six month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Procentual personal signal change of the fMRI-signal in the task related target areas. measurement during the processing of the socia-emotional tasks and before and after taking part in the virtual ball game (Cyberball). | — |
Secondary
| Measure | Time frame |
|---|---|
| General parameters of social-cognitive functions, measured by the emotional recognition task. Effects of taking part in the cyberball game in the manipulation check using the need-threat-scale. Group differences on the rejection sensitivity scale with pre-post-comparison. | — |
Countries
Germany
Contacts
Public ContactWolfgang Dau
LVR-Klinik Bonn, Abt. für Abhängigkeitserkrankungen und Psychotherapie
Outcome results
None listed