I50.9
Conditions
Interventions
Group 1: echocardiographic optimization of cardiac resynchronization therapy
Group 2: electrocardiographic optimization of cardiac resynchronization therapy
Sponsors
Deutsches Herzzentrum München, TU München
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: patients with planned CRT implantation, EF 120 ms
Exclusion criteria
Exclusion criteria: persistent atrial tachyarrhythmias, symptomatic bradycardias, relevant valvular disease, instable coronary artery disease, coronary intervention three months before study enrollment, significant comorbidities like chronic obstructive lung disease with chronic oxygen requirement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response to CRT was defined as a reduction of NYHA class by =1 score. The primary endpoint of the study was a comparison of this clinical response between group 1 and 2. NYHA-class was evaluated at the beginning of the study during the hospital stay before cardiac resynchronization therapy and at 3 months follow up in the hospital clinic with a patient history and documented in the patients records. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary endpoints were an echocardiographic comparison of improvement of EF, as well as a decrease of EDV, ESV and SDI between the two groups. Echocardiography (3-dimensional) was conducted at the beginning of the study during the hospital stay before cardiac resynchronization therapy and at 3 months follow up in the hospital clinic. | — |
Countries
Germany
Contacts
Public ContactCarolin Sonne
Deutsches Herzzentrum München
Outcome results
None listed