Lung function and airway hyper reactivity in late preterm and term infants after severe RSV infection in comparison to healthy controls

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004424

Enrollment

Registered

2013-12-20

Start date

2012-10-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J12.1 P07.2

Interventions

Group 1: preterm and term infants without lower respiratory tract infection, baby lung function

FEF (0.75) Group 2: term and preterm infants with lower respiratory tract infection, baby lung function testing, FEF (0.75)

Eligibility

Sex/Gender

All

Age

0 Months to 12 Months

Inclusion criteria

Inclusion criteria: for RSV group: positive RSV-test (ELISA/ PCR in nasopharyngeal aspirate) plus any of the follwing - wheezing - tachypnoea > 95. percentile of age - prolonged expiratory phase or crackles on auscultation - cyanosis (SpO2 < 92% without oxygen)

Exclusion criteria

Exclusion criteria: - congenital heart defect - pre-existing lung disease - immune deficiency - obvious skeletal thoracic malformation

Design outcomes

Primary

Measure	Time frame
Forced expiratory flow (0.75) at one year of age	—

Secondary

Measure	Time frame
forced expiratory flow (0.75) in term an preterm infants	—

Countries

Germany

Contacts

Public ContactMarcus Krüger

ZKJ, Universitätsklinikum Freiburg

marcus.krueger@uniklinik-freiburg.dexx4976127043000

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026