Determination of drugs and their metabolites in hospitalized patients.

Determination of drugs and their metabolites in hospitalized patients. - PEAK-001

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004392

Enrollment

1000

Registered

2012-10-15

Start date

2012-08-27

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infections C00-C97

Interventions

Group 1: Determination of plasma concentrations [ng/mL] of antineoplastic agents and antiinfectives in hospitalized patients receiving antineoplastic or antiinfective agents at time points when minimu

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: legal capacity, treatment with antineoplastic or antiinfective drugs

Exclusion criteria

Exclusion criteria: severe anemia

Design outcomes

Primary

Measure	Time frame
Plasma concentrations [ng/mL] of antineoplastic agents and antiinfectives in hospitalized patients receiving antineoplastic or antiinfective agents at time points when minimum and maximum plasma levels are expected. The plasma concentrations will be determined by liquid chromatography - tandem mass spectrometry or by immunological methods.	—

Secondary

Measure	Time frame
Variability of plasma concentrations [ng/mL] of antineoplastic agents and antiinfectives as a function of individual patient factors as height, weight, liver function and renal function.	—

Countries

Germany

Contacts

Public ContactMartin Wilhelm

Medizinische Klinik 5 - Hämatologie/Onkologie Klinikum Nürnberg

martin.wilhelm@klinikum-nuernberg.de09113983050

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026