Abnormalities of the formation of ethyl glucuronide in individuals with Gilbert's Disease or Crigler-Najjar-Syndrome.

Abnormalities of the formation of ethyl glucuronide in individuals with Gilbert's Disease or Crigler-Najjar-Syndrome. - GMS-EtG

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004363

Enrollment

100

Registered

2012-09-14

Start date

2012-10-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E80.5 E80.4

Interventions

Group 1: One-armed study After at least 2 days of abstinence from ethanol 100 test persons (50 men/women, if possible) are asked to drink 9 g of ethanol (0.1 l sparkling wine). This amount and drink w

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: - Gilbert's Disease or Crigler-Najjar-Syndrome - Age: 18+ - Good knowledge of spoken and written German - Capacity to consent - Two days of abstinence prior to the execution of the study

Exclusion criteria

Exclusion criteria: - other liver diseases - Diabetes mellitus - Kidney diseases - Cardio-vascular diseases - known pregnancy

Design outcomes

Primary

Measure	Time frame
Determination of ethyl glucuronide concentrations in the samples, interpretation of data in comparison to existing data from a former collective with no anomalies in metabolising.	—

Countries

Germany

Contacts

Public ContactLaura Huppertz

Institut für Rechtsmedizin Forensische Toxikologie

laura.huppertz@uniklinik-freiburg.de+49 761 203 6828

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026