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Impact of exercise intervention on neuropathic symptoms in patients with hematologic or oncological malignancies - PNP-pilot-study

Impact of exercise intervention on neuropathic symptoms in patients with hematologic or oncological malignancies - PNP-pilot-study - PNP-pilot-study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00004340
Enrollment
10
Registered
2013-01-04
Start date
2012-01-18
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C00-C97 G60-G64

Interventions

Group 1: Intervention group: The IG receives an 1 hour exercise program twice per week over 12 weeks including balance, strenght and endurance training.

Sponsors

Abtl I Medizinische Universitätsklinik Freiburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Haematological/oncological patients with symptoms of PNP regardless their malignant underlying disease or treatment status Age =18 years - Performance- Status Karnofsky- Index >60 (see 11.2) - Negative pregnancy test (urine or serum) for women of reproductive age - Signed informed consent - Geographical proximity (< 90 Minutes with transport)

Exclusion criteria

Exclusion criteria: Absolute: - Instable bone metastases - Myocardial infarction, Angina pectoris or heart disease (NYHA III-IV) in a time period of six months - Arterial hypertension, which is not treated adequately (in therapy >180mmHg systolic; >100mmHg diastolic) - Patients with an increased risk for thrombosis besides underlying disease Relative (inclusion or continuation after recovery possible): - Acute infection (=38,0°Celcius and/ or intravenously therapy with antibiotics) - Thrombocytes < 10x10^9/L - Leukocytes < 1x10^9/L

Design outcomes

Primary

MeasureTime frame
Sway path (cm) of centre of pressure [COP]: static postural control

Secondary

MeasureTime frame
Sway path (cm) of COP after perturbation: dynamic postural control Body sway (cm): dynamic postural control Nerve conduction velocity (m/s) and amplitude (mm) of stimulus response Value of FACT/GOG-Ntx- questionnaire Value of EORCT-QLQ-C30- questionnaire Performance (Watt) at the IAT h-1-RM (kg) Phase angle (°), FFM (kg, %), FAT (kg, %), BCM (%) MET of FFKA

Countries

Germany

Contacts

Public ContactSarah Kneis

Universitätsklinik Freiburg Abt. Hämatologie und Onkologie

sarah.kneis@uniklinik-freiburg.de0761/270-73240

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 19, 2026