C00-C97 G60-G64
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Haematological/oncological patients with symptoms of PNP regardless their malignant underlying disease or treatment status Age =18 years - Performance- Status Karnofsky- Index >60 (see 11.2) - Negative pregnancy test (urine or serum) for women of reproductive age - Signed informed consent - Geographical proximity (< 90 Minutes with transport)
Exclusion criteria
Exclusion criteria: Absolute: - Instable bone metastases - Myocardial infarction, Angina pectoris or heart disease (NYHA III-IV) in a time period of six months - Arterial hypertension, which is not treated adequately (in therapy >180mmHg systolic; >100mmHg diastolic) - Patients with an increased risk for thrombosis besides underlying disease Relative (inclusion or continuation after recovery possible): - Acute infection (=38,0°Celcius and/ or intravenously therapy with antibiotics) - Thrombocytes < 10x10^9/L - Leukocytes < 1x10^9/L
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sway path (cm) of centre of pressure [COP]: static postural control | — |
Secondary
| Measure | Time frame |
|---|---|
| Sway path (cm) of COP after perturbation: dynamic postural control Body sway (cm): dynamic postural control Nerve conduction velocity (m/s) and amplitude (mm) of stimulus response Value of FACT/GOG-Ntx- questionnaire Value of EORCT-QLQ-C30- questionnaire Performance (Watt) at the IAT h-1-RM (kg) Phase angle (°), FFM (kg, %), FAT (kg, %), BCM (%) MET of FFKA | — |
Countries
Germany
Contacts
Universitätsklinik Freiburg Abt. Hämatologie und Onkologie