D73.0 A41.9
Conditions
Interventions
Group 1: At baseline, the following parameters will be documented:
- demography (age, sex, body weight, body height)
- indication for splenectomy
- Charlson's comorbiditiy index and selected other
Sponsors
Universitätsklinikum FreiburgCentrum für chronische Immundefizienz (CCI)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients after splenectomy no documented spleen on imaging studies Hypo- or asplenia (Howell-Jolly-Bodies present)
Exclusion criteria
Exclusion criteria: no informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number and timing of infections requiring hospitalization after splenectomy | — |
Secondary
| Measure | Time frame |
|---|---|
| •Number and timing of Infections requiring intensive care therapy after splenectomy •Causal pathogen, focus of infection •Total mortality and mortality due to infection after splenectomy •Timing and type of required vaccination after splenectomy •Antibiotic prophylaxis •Concurrent or previous antineoplastic chemotherapy or immunosuppressive medication •other risk factors for infection (age, sex, smoking, alcohol, body weight) | — |
Countries
Germany
Contacts
Public ContactSiegbert Rieg
Centrum für Chronische Immundefizienz (CCI) und Abteilung Infektiologie, Klinik für Innere Medizin II; Universitätsklinikum Freiburg
Outcome results
None listed