Is the transnasal access for upper gastrointestinal endoscopy in routine use equal to the transoral route? A prospective, randomized trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004308

Enrollment

320

Registered

2012-08-17

Start date

2004-04-06

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases and conditions or disease- diagnostics, that necessitate upper GI- endoscopy: Unclear stomach- or upper abdominal pain Reflux- symptoms anemia- diagnostic Tumor- and varices- diagnostic Pre- und postoperative diagnostic

Interventions

Group 1: transnasal gastroscopy without sedation Group 2: transoral gastroscopy without sedation Group 3: transnasal gastroscopy without sedation after a previous transoral gastroscopy without sedati

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: group 1 and 2: Indication for upper GI Endoscopy; first examination ever group 3: Indication for upper GI Endoscopy; previous transoral upper GI- endoscopy without sedation

Exclusion criteria

Exclusion criteria: Clotting disorder; Patients with psychiatric diseases; patients under custodianship

Design outcomes

Primary

Measure	Time frame
Evaluation of procedure- tolerance according to a self- designed questionnaire which was filled out by the patient and a physician who was not involved in the procedure. Questions included: urge to gag, nausea, vomiting, acceptance of procedural technique, preference of access route (transoral/ transnasal) and sedation in a possible endoscopic procedure in the future. One- time evaluation directly after the procedure.	—

Measure

Time frame

Evaluation of procedure- tolerance according to a self- designed questionnaire which was filled out by the patient and a physician who was not involved in the procedure. Questions included: urge to gag, nausea, vomiting, acceptance of procedural technique, preference of access route (transoral/ transnasal) and sedation in a possible endoscopic procedure in the future. One- time evaluation directly after the procedure.

—

Secondary

Measure	Time frame
Patients' vote for transnasal or transoral access in case of an upper GI endoscopy in the future	—

Countries

Germany

Contacts

Public ContactBernd Krakamp

Krankenhaus Köln Merheim

krakampb@kliniken-koeln.de0049 221 8907 3442

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026