Assessment of Changes in Autonomic Cardiovascular Modulation, Brain Wave Activity, Neuropsychologic Function after repeated Heading in Soccer Players.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00004298

Enrollment

Registered

2012-08-07

Start date

2012-08-07

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy participants

Interventions

Group 1: Soccer players: Baseline-measurement, measurement after "pseudo-heading", measurement after heading

Eligibility

Sex/Gender

Male

Age

16 Years to 40 Years

Inclusion criteria

Inclusion criteria: healthy male soccer players within the age range of 16 and 40 years

Exclusion criteria

Exclusion criteria: Participants must not have organic or psychiatric disorders. In addition, people who need regular medication, will be excluded from participation in the study.

Design outcomes

Primary

Measure	Time frame
In soccer players, we will examine whether there are changes before and immediately after heading: (I) in the electroencephalogram (EEG) recording brain electrical activity (which would indicate a cerebral dysfunction), (II) in attention and concentration (Trail Making Test Part A & B, d2-test) - suggesting functional neuropsychological disorders of the brain (III) in the amount of cognitive effort, attention and concentration during testing, (which could be measured with an increase in catecholamine levels after heading), (IV) in the serum values of protein S-100B and NSE, (while an increase in values might indicate slight structural lesions of the brain). (V) in the sympathetic or parasympathetic modulation of heart rate and blood pressure (which would be most likely due to changes of the control functions of autonomic centers of the brain).	—

Measure

Time frame

In soccer players, we will examine whether there are changes before and immediately after heading: (I) in the electroencephalogram (EEG) recording brain electrical activity (which would indicate a cerebral dysfunction), (II) in attention and concentration (Trail Making Test Part A & B, d2-test) - suggesting functional neuropsychological disorders of the brain (III) in the amount of cognitive effort, attention and concentration during testing, (which could be measured with an increase in catecholamine levels after heading), (IV) in the serum values of protein S-100B and NSE, (while an increase in values might indicate slight structural lesions of the brain). (V) in the sympathetic or parasympathetic modulation of heart rate and blood pressure (which would be most likely due to changes of the control functions of autonomic centers of the brain).

—

Secondary

Measure	Time frame
For this study no secondary endpoints were defined.	—

Countries

Germany

Contacts

Public ContactJulia Köhn

Neurologische Universitätsklinik Erlangen

julia.koehn@uk-erlangen.de+49 9131 8544320

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026