Indication and outcome of hematopoietic stem cell transplantation in primary immunodeficiency with predominant hypogammaglobulinemia – a retrospective study

Indication and outcome of hematopoietic stem cell transplantation in primary immunodeficiency with predominant hypogammaglobulinemia – a retrospective study - StemPAD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004296

Enrollment

Registered

2012-08-27

Start date

2012-09-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

D80.9 D83.9 Z94.81 Z94.80

Interventions

Group 1: Non-interventional retrospective study: aquisition of clinical and laboratory parameters of PAD patients undergoing HSCT (Hematopoietic stem cell transplantation).

Eligibility

Sex/Gender

All

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: adult patients with primary immunodeficiency with predominant antibody deficiency having undergone allogeneic hematopoietic stem cell transplantation before 1st january 2013

Exclusion criteria

Exclusion criteria: age under 2 at transplantation, no informed consent to data collection

Design outcomes

Primary

Measure	Time frame
Number of adult PAD patients undergoing HSCT for any reason in cooperating centers worldwide.	—

Secondary

Measure	Time frame
immune reconstitution, mortality, morbidity after HSCT	—

Countries

Czechia, Denmark, France, Germany, Ireland, Italy, Netherlands, Norway, Poland, Portugal, Slovenia, Spain, Sweden, Switzerland, United Kingdom, United States

Contacts

Public ContactMarta Rizzi

Centrum für Chronische Immundefizienz (CCI), Universitätsklinikum Freiburg

marta.rizzi@uniklinik-freiburg.de+49 761 270 77640

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026