Z94.0 N18.5 G99.0
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Sedentary, non-smokers, having received their transplant at least a year previously with stable transplant function. Moreover, normotensive, aged between 18 to 60 years, both male and females, healthy sedentary nonsmokers volunteers are recruited.
Exclusion criteria
Exclusion criteria: Patients with unstable hypertension, diabetes mellitus, amyloidosis, congestive heart failure, recent myocardial infarction, unstable angina or musculoskeletal abnormality, who are using drugs that modify autonomic nervous system, as ß-blockers are excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Baroreflex sensitivity is assessed at baseline and after 6 month noninvasively, using The Task Force Monitor 3040i device (CNSystem, Graz, Austria) 24-h electrocardiogram monitoring for arrhythmias detection and heart rate variability analysis is assessed at baseline and after 6 month noninvasively, using the Burdick Vision Holter System from Cardiac Science (Bothell, Washington, USA) | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiorespiratory fitness is assessed at baseline and after 6 months using a symptom-limited cardiopulmonary exercise testing, under continuous ECG monitoring, on a treadmill (Trackmaster TM-400, Carollton TX, USA) using the Bruce protocol. | — |
Countries
Greece