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Effects of exercise training on cardiovascular and autonomic function among renal transplant recipients

Effects of exercise training on cardiovascular and autonomic function among renal transplant recipients - ExCART

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00004287
Enrollment
36
Registered
2012-08-03
Start date
2011-09-04
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Z94.0 N18.5 G99.0

Interventions

Group 1: Renal transplant recipients follow a 6- month mainly aerobic exercise training program. Patients are examined before and after the training period. Group 2: Renal transplants remain untrain

Sponsors

Aristotle University of Thessaloniki
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Sedentary, non-smokers, having received their transplant at least a year previously with stable transplant function. Moreover, normotensive, aged between 18 to 60 years, both male and females, healthy sedentary nonsmokers volunteers are recruited.

Exclusion criteria

Exclusion criteria: Patients with unstable hypertension, diabetes mellitus, amyloidosis, congestive heart failure, recent myocardial infarction, unstable angina or musculoskeletal abnormality, who are using drugs that modify autonomic nervous system, as ß-blockers are excluded

Design outcomes

Primary

MeasureTime frame
Baroreflex sensitivity is assessed at baseline and after 6 month noninvasively, using The Task Force Monitor 3040i device (CNSystem, Graz, Austria) 24-h electrocardiogram monitoring for arrhythmias detection and heart rate variability analysis is assessed at baseline and after 6 month noninvasively, using the Burdick Vision Holter System from Cardiac Science (Bothell, Washington, USA)

Secondary

MeasureTime frame
Cardiorespiratory fitness is assessed at baseline and after 6 months using a symptom-limited cardiopulmonary exercise testing, under continuous ECG monitoring, on a treadmill (Trackmaster TM-400, Carollton TX, USA) using the Bruce protocol.

Countries

Greece

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026