Non-interventional study to determine platelet reactivity in patients with STEMI / NSTE-ACS and percutaneous coronary revascularization on treatment with P2Y12 receptor antagonists

Non-interventional study to determine platelet reactivity in patients with STEMI / NSTE-ACS and percutaneous coronary revascularization on treatment with P2Y12 receptor antagonists - Kein Akronym

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004274

Enrollment

Registered

2012-07-25

Start date

2012-08-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I20.0 I21.0 I21.1 I21.2 I21.3 I21.4

Interventions

Group 1: Non-interventional study in patients treated with a loading dose of prasugrel 60 mg as regular care Group 2: Non-interventional study in patients treated with a loading dose of ticagrelor 1

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Are at least 18 years of age - Subjects with ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation acute coronary syndrome (NSTE-ACS) admitted at Universitäts-Herzzentrum Freiburg-Bad Krozingen at Bad Krozingen - Indication for urgent percutaneous coronary revascularization

Exclusion criteria

Exclusion criteria: - Medical or mental condition preventing to provide written informed consent - Acute clinical relevant bleeding - Treatment with a GP IIb/IIIa inhibitor wihin one week prior or during PCI

Design outcomes

Primary

Measure	Time frame
Platelet reactivity (PRU) at PCI determined by VerifyNow P2Y12 assay	—

Secondary

Measure	Time frame
Platelet reactivity at PCI and at day 1 after PCI determined by light transmission aggregometry Platelet reactivity at PCI and at day 1 after PCI determined by impedance aggregometry (MEIA test) Platelet reactivity at day 1 after PCI determined by VerifyNow P2Y12 assay	—

Countries

Germany

Contacts

Public ContactDietmar Trenk

Universitäts-Herzzentrum Freiburg - Bad Krozingen, Klinik für Kardiologie und Angiologie II, Abt. Klinische Pharmakologie

dietmar.trenk@universitaets-herzzentrum.de+49 7633 402 2481

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026