Nonlinear mechanics of the respiratory system in controlled ventilated patients of the anesthesiological Intensive Care Unit

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00004263

Enrollment

Registered

2012-07-19

Start date

2012-08-23

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute respiratory distress syndrome (ARDS) J80

Interventions

Group 1: At the mechanically ventilated patient pressure and flow rate data are collected from the ventilator. After 10 min of data recording, PEEP will be increased by 5 mbar for 10 min and subsequen

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: controlled mechanically ventilated patients with ARDS

Exclusion criteria

Exclusion criteria: age < 18 years, pregnancy, missing informed consent, terminal phase of disease

Design outcomes

Primary

Measure	Time frame
The temporal courses of airway pressure and flow rate are recorded from the ventilator. These data are processed to the intratidal profile of respiratory system compliance in an offline analysis.	—

Secondary

Measure	Time frame
Expiratory CO2 and blood pressures as determined by the available monitoring system are protocollized. Data analysis is performed offline after the meaurements.	—

Countries

Germany

Contacts

Public ContactStefan Schumann

Anästhesiologische Universitätsklinik Freiburg

stefan.schumann@uniklinik-freiburg.de0761/27023290

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026