Respiratory Muscle Assessment in Acute Guillain-Barré-Syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004236

Enrollment

Registered

2012-07-09

Start date

2007-10-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G61.0

Interventions

Group 1: Respiratory muscle evaluation using various assessment-techniquies in patients with acute Guillain Barré Syndrome

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Acute Guillain-Barré-Syndrome

Exclusion criteria

Exclusion criteria: pre-existing respiratory muscle disorders pre-existing neuromuscular disease other Guillain-Barré-Syndrome severe restrictive chest disease severe respiratory infectious disease obstructive lung function impairment (FEV1/FVC10mg) electronically implanted devices metal implants in the head/neck region coagulation disorder (Quick<30%) pregnancy severe obstructive sleep apnea

Design outcomes

Primary

Measure	Time frame
Objectively assessed respiratory muscle affection of the diaphragm using magnetic phrenic nerve stimulation in patients with Guillain-Barrè Syndrome within the first week of disease onset.	—

Secondary

Measure	Time frame
What is the time course of respiratory muscle affection in acute Guillain-Barré Syndrome? Are there better prognostic markers than vital capacity measurements in acute Guillain-Barrè Syndrome to assess respiratory muscle affection? Is vital capacity assessment linked to indices of respiratory muscle function?	—

Countries

Germany

Contacts

Public ContactHans-Joachim Kabitz

Uniklinik Freiburg Abt. Pneumologie

hans-joachim.kabitz@uniklinik-freiburg.de004076127074070

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026