Yolk Sac Screening Trial for Detecting Fetal Aneuploidies at Very Early Pregnancy

Yolk Sac Screening Trial for Detecting Fetal Aneuploidies at Very Early Pregnancy - YoSST

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00004216

Enrollment

11543

Registered

2012-09-11

Start date

2013-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Q99.9

Interventions

Group 1: Sonographical estimation of the yolk sac diameter, the crown-rump-length

aswell as measuring the blood serum concentration of PAPP-A in the maternal blood

karyotyping in case of miscarriage or abortion

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Pregant woman at age 18 or older after given consent

Exclusion criteria

Exclusion criteria: Crown-rump-length > 84mm

Design outcomes

Primary

Measure	Time frame
Sonographical estimation of the yolk sac diameter according to the crown-rump-length, aswell as validating the blood serum concentration of PAPP-A in the maternal blood and observing the fetal outcome - in case of miscarriage by karyotyping - in case of abortion by cartyotyping - in case of live birth clinically for unconspicious examination U2	—

Countries

Germany

Contacts

Public ContactPeter Schmidt

Medizinische Hochschule Hannover, Abteilung für Frauenheilkunde und Geburtshilfe

info@dr-schmidt.info0511 / 532 6441

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026