Effects of DBS on cognition of ppatients with essential tremor

Effects of DBS on cognition of ppatients with essential tremor - ColTrem V

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00004210

Enrollment

Registered

2012-06-27

Start date

2012-06-28

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G25.0

Interventions

Group 1: Patient with optimal settings of DBS under which motor symptoms are best under control Group 2: Patients without DBS Group 3: Patients with ineffective DBS

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Subjects with essential tremor treated by DBS at least 3 months ago Localization of electrodes in the Vim/Vlp or the posterior subthalamic Area (PSA) Tolerable Tremor after switching off stimulation Age between 18 and 80 years Disease duration longer than 5 years

Exclusion criteria

Exclusion criteria: Subjects with other severe neurological disease Irregularities in cranial imaging Subjects suffering from rest tremor or bradykinesia on one side DemTect < 9 Subjects suffering from depression

Design outcomes

Primary

Measure	Time frame
Cognitive assessment through questionnaires: 1. Stroop-Test, 2. Hamilton anxiety rating scale (HARS), 3. Verbal fluency. 1+3 are tested in every condition and 2 is tested only once	—

Secondary

Measure	Time frame
Tremor improvement by DBS, measured by TRG Essential Tremor Rating Assessment Scale	—

Countries

Germany

Contacts

Public ContactDavid J. Pedrosa

Universitätsklinik Köln Klinik und Poliklinik für Neurologie AG Bewegungsstörungen

david.pedrosa@uk-koeln.de(+49) 221- 478 4014

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026