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Relation of MUscular contractions to mechanical STrains in the human tibia during different locomotive activities

Relation of MUscular contractions to mechanical STrains in the human tibia during different locomotive activities - MUST

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00004207
Enrollment
5
Registered
2012-07-04
Start date
2012-07-05
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Volunteers

Interventions

Group 1: So far here is no evidence on the interaction of gravitational forces with muscle forces and its influence on deformation of bone. Aim of the study is to determine mechanical deformation of t

Sponsors

Deutsches Zentrum für Luft- und Raumfahrt Institut für Luft- und Raumfahrtmedizin Weltraumphysiologie
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 55 Years

Inclusion criteria

Inclusion criteria: • five male healthy subjects • age between 20 and 55 years • Body mass index (BMI): 20 -30 kg/m2 • signed consent form

Exclusion criteria

Exclusion criteria: • Apart from the PI of the study, Prof. Jörn Rittweger, no further co-workers of DLR or Cologne University Hospital, or financially dependent persons may participate as test subjects • corticalis-diameter under 4 mm at site of planned screw insertion • muscle or joint disorders • fractures of the lower extremity in the last 12 months • metall-implants • participation in a different clinical study within 2 months prior to start of study • decreased blood-coagulation • unwanted reactions on local anaesthetic in the past • operations on the tibia in the last 12 months • Any other condition that leads to exclusion from the study in the eyes of the clinical investigator

Design outcomes

Primary

MeasureTime frame
Assessment of the influence of muscle force and gravitational force on the deformation of bone (tibia) with a vicon-camerasystem, motion capturing, electromyography, ultrasound und several devices for force measurements.

Countries

Germany

Contacts

Public ContactJörn Rittweger

Deutsches Zentrum für Luft- und Raumfahrt Institut für Luft- und Raumfahrtmedizin Weltraumphysiologie

joern.rittweger@dlr.de0049 2203 601 3060

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026